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Michael Mannstadt, MD

Massachusetts General Hospital, Harvard Medical School, Boston, MA

BACKGROUND: Dr. Mannstadt is a clinical endocrinologist at the Massachusetts General Hospital/Harvard Medical School in Boston and his endocrine practice focuses on diseases affecting bone metabolism and mineral ion homeostasis. He is also working as physician-scientist in the laboratory, where his research is focused on studying the regulation of parathyroid hormone (PTH), the major regulator of calcium homeostasis, by the parathyroid glands. Through the identification of novel disease-causing mutations in the parathyroid-specific transcription factor GCMB in patients with hypoparathyroidism, he and his colleagues have identified new tools to study further parathyroid gland development and function.